منابع مشابه
Mitotic Entry: Tipping the Balance
In the eukaryotic cell cycle, the G2-M transition is regulated by a counteracting kinase/phosphatase mechanism. A novel player, Tome-1, has now been found to trigger entry into mitosis by interfering with this kinase/phosphatase 'switch'.
متن کاملTipping the balance in glomerulonephritis.
M any forms of glomerulonephritis (GN) are believed to be autoimmune in origin, with both humoral and cellular immune responses directed against resident or planted glomerular antigens. In a proportion of cases the antigens are known, such as the 3 chain of type IV collagen constituent of the glomerular basement membrane (GBM) and the immune target in anti-GBM disease (1). In some diseases, ant...
متن کاملTipping the balance toward trophoblast development.
Understanding the development of the human trophoblast lineage and placentation is a challenge. Ethical issues prevent the most direct experimentation. Animal models have provided considerable insight, but species differences exist and knowledge of key regulatory events in human development is missing, which precludes an appreciation of conserved processes. In the mouse, it is possible to captu...
متن کاملStriking the Right Balance Determines TB or Not TB
Mycobacterium tuberculosis continues to be one of the most successful pathogens on earth. Upon inhalation of M. tuberculosis by a healthy individual, the host immune system will attempt to eliminate these pathogens using a combination of immune defense strategies. These include the recruitment of macrophages and other phagocytes to the site of infection, production of cytokines that enhance the...
متن کاملBenefits versus risks of computed tomography: tipping the balance.
Journal of Thoracic Imaging (ISSN: 0883-5993) is published quarterly by Lippincott Williams & Wilkins, at 16522 Hunters Green Parkway, Hagerstown, MD 21740-2116. Business and production offices are located at Two Commerce Square, 2001 Market Street, Philadelphia, PA 19103. Periodicals postage paid at Hagerstown, MD and at additional mailing offices. Copyright r 2010 by Lippincott Williams & Wil...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Reviews Immunology
سال: 2014
ISSN: 1474-1733,1474-1741
DOI: 10.1038/nri3722